Concanavalin A (Con A) Solution (500X)
Concanavalin A (Con A) Solution (500X)
Author: ApexBio
shortsummary:
Concanavalin A (Con A) is a potent leukocyte mitogen, which can be used for in vitro activation of human and mouse leukocytes.
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In stock
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Blue ice
description:
Concanavalin A (Con A), derived from Canavalia ensiformis (Concanavalin), is a plant lectin protein (Mw = 104 kDa). At pH ≥ 7.0, Con A exists as a homotetrameric structure consisting of four subunits with a molecular weight of 26 kDa. Under acidic conditions (pH 4.5-5.5), Con A dissociates into an activated dimer structure (52 kDa), and acetylation, succinylation, or other derivatives can also produce stable dimer structures. Each subunit binds a Ca2+ and a Mn2+, contains a sugar-binding site, and when the metal ions bind to Con A, it can bind various glycoproteins, glycolipids and α-D-glucose and a-D-mannose moieties in sugars, which is suitable for carbohydrate research, glycoprotein purification, enzyme tagging, cell membrane research, cell agglutination, cell culture and cell typing studies.
Concanavalin A (Con A) Solution (500X) PMC11456997related websites:
APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 18946 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.
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